Second Vial - Sea turned to blood
Vial - God's Judgement on the Papacy (Second Beast)
Revelation 16:3 - And the second angel poured out his vial upon the sea; and it became as the blood of a dead man: and every living soul died in the sea.
Revelation 11:6 - These have power to shut heaven, so that no rain falls in the days of their prophecy; and they have power over waters to turn them to blood, and to strike the earth with all plagues, as often as they desire.
Revelation 13:1 - Then I stood on the sand of the sea. And I saw a beast rising up out of the sea, having seven heads and ten horns, and on his horns ten crowns, and on his heads a blasphemous name.
The Second Vial caused the large scale massacres and dreadful wars that followed the French Revolution. France became drenched in its own blood, and the whole territory converted into a vast slaughterhouse. It has been computed that 2,000,000 people were massacred in France within 3 years after it became a Republic of which 250,000 were women, 230,000 children, and 24,000 catholic priests.
Long after the Revolutionary massacres had ceased, French blood still continued to flow in torrents, and from the accession of Napoleon to the Consular and Imperial powers, till his overthrow by the combined forces of Europe, it successively fertilized the soil of every country in Europe.
The Sea on which the second vial is poured out turning it to blood, is understood to represent the maritime powers and colonies of Papal Christendom.
The democratic revolutionary spirit of France and the naval force of England contributed to effect the purpose of Divine Providence. First, the Isle of Haiti, the most flourishing of the French colonies, being infected by the like infidel principles, was lost after a servile war of twelve years, in which 60,000 blacks were slaughtered.
Then, for 20 years, the fleet of England (preserved and directed by the same good providence of God) wasted in all directions the ships, commerce, and maritime colonies of France, and of her allies, Holland and Spain. Their fleet was destroyed in 1793, at Toulon, by Admiral Samuel Hood; by whom also Corsica, and nearly all the Spanish and West Indian Islands were taken in 1794. In 1795 followed the naval victory of L'Orient, and the capture of the Cape of Good Hope.
The Victory in 1797 off Cape St. Vincent was quickly succeeded by that of Camperdown over the Dutch fleet. Then followed Lord Nelson's three mighty victories of the Nile in 1798, of Copenhagen in 1801, and in 1805 of Trafalgar. Viewing the losses suffered by France from 1793 to the end of 1815, we find that nearly 600 vessels of war, besides numerous ships of commerce, were destroyed, together with a large proportion of their officers and men.
The world's history does not furnish such a period of naval war and bloodshed till that time. The sea became as the blood of a dead man (Revelation 16:3). Finally, when the maritime power of the papal nations had been swept away by English victories, the Spanish colonies of South America threw off their allegiance, after another scene of carnage, only paralleled by those before described; the Brazilians also were separated from Portugal, and so the prediction was complete: as regarded the papal European colonies, they became dead.
Protestant England and Catholic Europe strive together upon the ocean. The old Catholic powers, those which in the past have been the vile instruments of Papal wrong, the nations whose kings have committed fornication with the great spiritual harlot, suffer the loss in this long and deadly struggle of 600 ships of the Line, the largest war vessels that then went to sea, besides the 1000s of ships of war of smaller size. At the close of the contest, the naval power of Catholic Europe had been swept from the ocean by Protestant England.